Influence of Lung Function and Sleep-disordered Breathing on All-Cause Mortality. A Community-based Study

RATIONALE: Whether sleep-disordered breathing (SDB) severity and diminished lung function act synergistically to heighten the risk of adverse health outcomes remains a topic of significant debate. OBJECTIVES: The current study sought to determine whether the association between lower lung function and mortality would be stronger in those with increasing severity of SDB in a community-based cohort of middle-aged and older adults. METHODS: and apnea-hypopnea index (AHI) as the primary exposure indicators along with several potential confounders. MEASUREMENTS AND MAIN RESULTS: , 0.004). CONCLUSIONS: Lung function was associated with risk for all-cause mortality. The incremental contribution of lung function to mortality diminishes with increasing severity of SDB.