A limited treadmill exercise test before hospital discharge after acute myocardial infarction predicted one-year mortality, which was 27% in patients with S-T depression versus 2.1% without (P<0.001).
Cohort (n=210)
Acute myocardial infarction (n=210)
Limited treadmill exercise test (S-T segment depression) vs No changes in the S-T segment during exercise
One-year mortality, p=<0.001
Absolute Event Rate: 27% vs 2.1%
p-value: p=<0.001
The prognostic value of a limited treadmill exercises test performed one day before hospital discharge after acute myocardial infarction was studied in 210 consecutive patients who had no over heart failure and had been free of chest pain for at least four days. No complications occurred. During a one-year follow-up period 28 of 43 patients (65 per cent) who had chest pain during the test reported angina, as compared with 60 of 167 (36 per cent) who had no chest pain during test (P less than 0.001). The one-year mortality rates were 2.1 per cent (three of 146) in patients without changes in the S-T segment during exercise and 27 per cent (17 of 64) in those with depression of the S-T segment (P less than 0.001). Sudden death occurred in one of 146 (0.7 per cent) patients who showed no change in the S-T segment and in 10 of 64 (16 per cent) with depression of the segment (P less than 0.001). Thus, a limited treadmill exercise test performed before hospital discharge after acute myocardial infarction is safe and can predict mortality in the subsequent year.
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Pierre Théroux
Roche (Switzerland)
David D. Waters
General Cardiology
C Halphen
Montreal Heart Institute
New England Journal of Medicine
Université de Montréal
Montreal Heart Institute
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Théroux et al. (Thu,) conducted a cohort in Acute myocardial infarction (n=210). Limited treadmill exercise test (S-T segment depression) vs. No changes in the S-T segment during exercise was evaluated on One-year mortality (p=<0.001). A limited treadmill exercise test before hospital discharge after acute myocardial infarction predicted one-year mortality, which was 27% in patients with S-T depression versus 2.1% without (P<0.001).
synapsesocial.com/papers/6a088ce6ae7f011b61ddf194 — DOI: https://doi.org/10.1056/nejm197908163010701