Is Isolated Low High-Density Lipoprotein Cholesterol a Cardiovascular Disease Risk Factor?

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1A Null Mutation in Human <i>APOC3</i> Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection2008 · 694 citations
2. 2Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge1972 · 32,546 citations
3. 3Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?1990 · 999 citations
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5. 5Elevated Remnant Cholesterol Causes Both Low-Grade Inflammation and Ischemic Heart Disease, Whereas Elevated Low-Density Lipoprotein Cholesterol Causes Ischemic Heart Disease Without Inflammation2013 · 704 citations