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MUCH time, effort and expense is spent in the study of the effects of drugs, but little attention is devoted to whether or not patients take them as directed. And yet the drug defaulter is part of every practice, and to prescribe effectively, physicians should know how to recognize and reduce factors that contribute to poor compliance.Frequency and Types of NoncomplianceNoncompliance has been observed in the treatment of a wide variety of diseases. A recent review of over 50 studies1 found that complete failure to take medication often occurred in between 1/4 and over 1/2 of all outpatients. . . .
Barry Blackwell (Thu,) studied this question.