May 26, 2016Open Access
Location, Location, Location: Five Facts about Tissue Tropism and Pathogenesis
Key Result
Tissue tropism significantly impacts disease severity, transmission, and treatment efficacy in infectious diseases such as Staphylococcus aureus, Trypanosoma brucei, and influenza.
PICO
P
Population
Infectious diseases (Staphylococcus aureus, Trypanosoma brucei, Influenza)
Limitations
- We cannot yet account for all the factors involved in tissue tropism.
- Fine-scale differences in host tissue chemistry, metabolism, waste production, and local immune responses are still being identified.
- The paths used by pathogens to reach their ultimate tissue niche are often not fully understood.
Abstract
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