Mammalian glycosidases. 4. The intracellular localization of β-galactosidase, α-mannosidase, β-N-acetylglucosaminidase and α-l-fucosidase in mammalian tissues

The lysosome theory, whether it is true or not, certain mouse tumours, however, had a considerembodies biological,features of general importance. able proportion of their P-glucuronidase activity in In its original form (de Duve, Pressman, Gianetto, the soluble fraction. No appreciable fraction of the Wattiaux & Appelmans, 1955) this theory favours enzyme activity appeared to be in the nucleus. the view that 'lysosomes form a single population