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A brief review of the biochemistry and physiological functions of the renin-angiotensin system is presented. A critical analysis is given of the various methods, both bioassay and radioimmunoassay, for measuring plasma renin and angiotensin levels. With the development of radioimmunoassay, specific, precise and rapid measurements of renin and angiotensin levels may now be made. Various factors that may influence the plasma level of renin are discussed, and the clinical applications for plasma renin measurements are listed.
Johnston et al. (Fri,) studied this question.