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The driver landscape in AML reveals distinct molecular subgroups that reflect discrete paths in the evolution of AML, informing disease classification and prognostic stratification. (Funded by the Wellcome Trust and others; ClinicalTrials.gov number, NCT00146120.).
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Elli Papaemmanuil
Moritz Gerstung
Lars Bullinger
New England Journal of Medicine
University of Cambridge
Memorial Sloan Kettering Cancer Center
KU Leuven
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Papaemmanuil et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69d7573ab54ccf0cfef30e8c — DOI: https://doi.org/10.1056/nejmoa1516192