Patients with Pulmonary Arterial Hypertension (PAH)
PAH-SYMPACT® questionnaire (patient-reported outcome instrument)
Content saturation, concept validity, and ePRO usabilitypatient reported
The PAH-SYMPACT questionnaire is a newly developed patient-reported outcome instrument that demonstrates concept validity for assessing symptoms and impacts in PAH patients.
The PAH-SYMPACT® was shown to capture symptoms and their impacts relevant to PAH patients, demonstrating content saturation, concept validity, and ePRO usability. Final content and psychometric validation of the instrument will be based on the results of an ongoing Phase IIIb clinical trial in PAH patients.
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Deborah H. McCollister
Shannon Shaffer
David B. Badesch
Respiratory Research
University of Colorado Denver
Actelion (Switzerland)
Health Economics and Outcomes Research (United Kingdom)
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McCollister et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d570a075589c71d767ddca — DOI: https://doi.org/10.1186/s12931-016-0388-6