Transrectal Ultrasonography for Prostatic Cancer: Its Value in Staging and Monitoring the Response to Radiotherapy and Chemotherapy

No AccessJournal of Urology1 May 1985Transrectal Ultrasonography for Prostatic Cancer: Its Value in Staging and Monitoring the Response to Radiotherapy and Chemotherapy Awato Fujino, and Peter T. Scardino Awato FujinoAwato Fujino More articles by this author , and Peter T. ScardinoPeter T. Scardino More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)49236-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Current methods to evaluate the size and local extent of prostatic cancer are imprecise. Quantitative assessments of changes after therapy are unreliable. We have used transrectal ultrasonography in 50 patients with clinically localized prostatic cancer to determine the value of this imaging technique in staging the local tumor and in monitoring the response of the tumor to therapy. Transverse images of the prostate were obtained at 5mm. intervals, and were used to determine the size and shape of the prostate, irregularity or discontinuity of the capsule, extracapsular extension of tumor and invasion into the seminal vesicles. Ultrasonography proved highly accurate in staging. Among 18 previously untreated patients whose tumor appeared to be confined to the prostate by rectal examination 8 (44 per cent) had extension beyond the prostate by ultrasonography, which was confirmed by operative findings. Serial ultrasonograms were performed before and after definitive radiotherapy in 7 patients and chemotherapy in 6 patients. In response to therapy the prostate decreased in size and resumed a more normal, symmetrical shape, the capsule reformed and thickened, the degree of extracapsular extension diminished and the seminal vesicles became normal. Maximal reduction in the size of the prostate usually occurred by 9 months after radiotherapy and by 3 months after chemotherapy. In patients with prostatic cancer transrectal ultrasonography is highly accurate in staging and offers an objective monitor of the response to therapy. © 1985 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByRodriguez E, Skarecky D, Narula N and Ahlering T (2018) Prostate Volume Estimation Using the Ellipsoid Formula Consistently Underestimates Actual Gland SizeJournal of Urology, VOL. 179, NO. 2, (501-503), Online publication date: 1-Feb-2008.McSherry S, Levy F, Schiebler M, Keefe B, Dent G and Mohler J (2018) Preoperative Prediction of Pathological Tumor Volume and Stage in Clinically Localized Prostate Cancer: Comparison of Digital Rectal Examination, Transrectal Ultrasonography and Magnetic Resonance ImagingJournal of Urology, VOL. 146, NO. 1, (85-89), Online publication date: 1-Jul-1991.Terris M and Stamey T (2018) Determination of Prostate Volume by Transrectal UltrasoundJournal of Urology, VOL. 145, NO. 5, (984-987), Online publication date: 1-May-1991.Andriole G, Coplen D, Mikkelsen D and Catalona W (2018) Sonographic and Pathological Staging of Patients with Clinically Localized Prostate CancerJournal of Urology, VOL. 142, NO. 5, (1259-1261), Online publication date: 1-Nov-1989.Waterhouse R and Resnick M (2018) The Use of Transrectal Prostatic Ultrasonography in the Evaluation of Patients with Prostatic CarcinomaJournal of Urology, VOL. 141, NO. 2, (233-239), Online publication date: 1-Feb-1989.Andriole G, Kavoussi L, Torrence R, Lepor H and Catalona W (2018) Transrectal Ultrasonography in the Diagnosis and Staging of Carcinoma of the ProstateJournal of Urology, VOL. 140, NO. 4, (758-760), Online publication date: 1-Oct-1988.Cooner W, Mosley B, Rutherford C, Beard J, Pond H, Bass R and Terry W (2018) Clinical Application of Transrectal Ultrasonography and Prostate Specific Antigen in the Search for Prostate CancerJournal of Urology, VOL. 139, NO. 4, (758-761), Online publication date: 1-Apr-1988.Resnick M (2018) Editorial CommentJournal of Urology, VOL. 139, NO. 4, (761-761), Online publication date: 1-Apr-1988. (2018) Reply by AuthorsJournal of Urology, VOL. 139, NO. 4, (761-761), Online publication date: 1-Apr-1988. Volume 133Issue 5May 1985Page: 806-810 Advertisement Copyright & Permissions© 1985 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Awato Fujino More articles by this author Peter T. Scardino More articles by this author Expand All Advertisement PDF DownloadLoading ...