A system utilizing light diffraction techniques and a penmotor system successfully controlled muscle length, sarcomere length, and force in rat cardiac trabeculae.
A system that makes control of muscle length (ML), sarcomere length (SL), and force (F) possible in striated muscle preparations is described. SL was measured by light diffraction techniques and two diffractometers. Control was performed by influencing ML with a penmotor system with a frequency response of 190 Hz. SL or F could be controlled by interrupting the internal position (i.e., ML) feedback of the motor and by closing the respective loop. Velocity feedback of the motor through an internal velocity coil was maintained in all cases for optimal damping. Steady-state error of the system was minimized by an integrating loop filter. The feedback path was selected by means of potentiometers or analog switches. Electronic stops in the circuit protected the muscle against excessive stretch and load. A microprocessor-based average-response computer could be used for feedforward control to eliminate noise or to analyze longitudinal uniformity of the muscle. Responses of rat cardiac trabeculae during SL and F control are shown. Transient behavior of SL and F during control and measures to eliminate the transients are discussed.
Heuningen et al. (Mon,) conducted a other in Striated muscle physiology. System for control of muscle length, sarcomere length, and force was evaluated. A system utilizing light diffraction techniques and a penmotor system successfully controlled muscle length, sarcomere length, and force in rat cardiac trabeculae.