Polydopamine Hollow Nanoparticle Functionalized with N‐diazeniumdiolates as a Nitric Oxide Delivery Carrier for Antibacterial Therapy

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Abstract

A biocompatible nitric oxide (NO) delivery nanoplatform, whose structure is a hollow nanoparticle composed of polydopamine backbone and diazeniumdiolates functional groups, is developed for antibacterial therapy. This platform liberates high NO quantitis and exerts the antibacterial activity with excellent biocompatibility thus being promising for treating bacterial infections.

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Authors

Dongsik Park

University of Akron

Jihoon Kim

Andong National University

Yeong Mi Lee

Pohang University of Science and Technology

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Advanced Healthcare Materials

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Pohang University of Science and Technology

Institute for Basic Science

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Park et al. (Wed,) studied this question.

synapsesocial.com/papers/69fe4a5c0e9c66b9de553be9 — DOI: https://doi.org/10.1002/adhm.201600150

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Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria· 2015 · 1,557 citations
Nitric oxide and the immune response· 2001 · 3,408 citations
Mussel-Inspired Surface Chemistry for Multifunctional Coatings· 2007 · 10,708 citations
Overview of Nosocomial Infections Caused by Gram-Negative Bacilli· 2005 · 1,414 citations
Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives· 1994 · 1,356 citations

Polydopamine Hollow Nanoparticle Functionalized with N‐diazeniumdiolates as a Nitric Oxide Delivery Carrier for Antibacterial Therapy

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Discussion

Cite this study

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