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Cryptochromes are flavoprotein photoreceptors with multiple signaling roles during plant de-etiolation and development. Arabidopsis cryptochromes (cry1 and cry2) absorb light through an oxidized flavin (FAD ox ) cofactor which undergoes reduction to both FADH and FADH -redox states. Since the FADH redox state has been linked to biological activity, it is important to estimate its concentration formed upon illumination in vivo.
Procopio et al. (Tue,) studied this question.