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We develop a computational approach to study tumor-infiltrating immune cells and their interactions with cancer cells. Our resource of immune-infiltrate levels, clinical associations, as well as predicted therapeutic markers may inform effective cancer vaccine and checkpoint blockade therapies.
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Bo Li
Eric A. Severson
Jean‐Christophe Pignon
Genome biology
Harvard University
Brigham and Women's Hospital
Dana-Farber Cancer Institute
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Li et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69d8cc1417a1cc0598d1882d — DOI: https://doi.org/10.1186/s13059-016-1028-7