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Among patients with platinum-sensitive, recurrent ovarian cancer, the median duration of progression-free survival was significantly longer among those receiving niraparib than among those receiving placebo, regardless of the presence or absence of gBRCA mutations or HRD status, with moderate bone marrow toxicity. (Funded by Tesaro; ClinicalTrials.gov number, NCT01847274 .).
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Mansoor R. Mirza
Bradley J. Monk
Jørn Herrstedt
New England Journal of Medicine
University College London
Dana-Farber Cancer Institute
University of Arizona
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Mirza et al. (Sat,) studied this question.
www.synapsesocial.com/papers/69d77af93fae90fd6048f47c — DOI: https://doi.org/10.1056/nejmoa1611310