A hospital's proportion of inappropriate nonacute PCIs was not associated with in-hospital mortality compared to lowest-tertile hospitals (OR 1.12; 95% CI 0.88-1.43; P=0.35).
Cohort (n=203,531)
Yes
Does a hospital's proportion of inappropriate PCIs affect in-hospital mortality, bleeding, or medical therapy at discharge in patients undergoing nonacute PCI?
A hospital's proportion of inappropriate PCIs is not associated with in-hospital procedural outcomes, indicating that appropriateness and procedural execution are independent dimensions of PCI quality.
Effect estimate: OR 1.12 (95% CI 0.88-1.43)
p-value: p=0.35
BACKGROUND: Measurement of hospital quality has traditionally focused on processes of care and postprocedure outcomes. Appropriateness measures for percutaneous coronary intervention (PCI) assess quality as it relates to patient selection and the decision to perform PCI. The association between patient selection for PCI and processes of care and postprocedural outcomes is unknown. METHODS AND RESULTS: We included 203 531 patients undergoing nonacute (elective) PCI from 779 hospitals participating in the National Cardiovascular Data Registry (NCDR) CathPCI Registry between July 2009 and April 2011. We examined the association between a hospital's proportion of nonacute PCIs categorized as inappropriate by the 2009 Appropriate Use Criteria (AUC) for Coronary Revascularization and in-hospital mortality, bleeding complications, and use of optimal guideline-directed medical therapy at discharge (ie, aspirin, thienopyridines, and statins). When categorized as hospital tertiles, the range of inappropriate PCI was 0.0% to 8.1% in the lowest tertile, 8.1% to 15.2% in the middle tertile, and 15.2% to 58.6% in the highest tertile. Compared with lowest-tertile hospitals, mortality was not significantly different at middle-tertile (adjusted odds ratio OR, 0.93; 95% confidence interval CI, 0.73-1.19) or highest-tertile hospitals (OR, 1.12; 95% CI, 0.88-1.43; P=0.35 for differences between tertiles). Similarly, risk-adjusted bleeding did not vary significantly (middle-tertile OR, 1.13; 95% CI, 1.02-1.16; highest-tertile OR, 1.02; 95% CI, 0.91-1.16; P=0.07 for differences between tertiles) nor did use of optimal medical therapy at discharge (85.3% versus 85.7% versus 85.2%; P=0.58). CONCLUSIONS: In a national cohort of nonacute PCIs, a hospital's proportion of inappropriate PCIs was not associated with in-hospital mortality, bleeding, or medical therapy at discharge. This suggests PCI appropriateness measures aspects of hospital PCI quality that are independent of how well the procedure is performed. Therefore, PCI appropriateness and postprocedural outcomes are both important metrics to inform PCI quality.
Bradley et al. (Tue,) conducted a cohort in Nonacute (elective) percutaneous coronary intervention (n=203,531). High proportion of inappropriate PCIs (highest tertile) vs. Low proportion of inappropriate PCIs (lowest tertile) was evaluated on In-hospital mortality (OR 1.12, 95% CI 0.88-1.43, p=0.35). A hospital's proportion of inappropriate nonacute PCIs was not associated with in-hospital mortality compared to lowest-tertile hospitals (OR 1.12; 95% CI 0.88-1.43; P=0.35).