In US outpatient cardiology practices, use of guideline-recommended heart failure therapies varied widely, with a median of 27% of eligible patients receiving all indicated therapies.
Cohort (n=15,381)
Yes
What is the rate of use of guideline-recommended therapies for heart failure in the US outpatient cardiology practice setting?
This national registry demonstrates substantial variation and underutilization of specific guideline-directed heart failure therapies, particularly aldosterone antagonists and device therapy, in US outpatient cardiology practices.
Background— Few data exist regarding contemporary care patterns for heart failure (HF) in the outpatient setting. IMPROVE HF is a prospective cohort study designed to characterize current management of patients with chronic HF and ejection fraction ≤35% in a national registry of 167 US outpatient cardiology practices. Methods and Results— Baseline patient characteristics and data on care of 15381 patients with diagnosed HF or prior myocardial infarction and left ventricular dysfunction were collected by chart abstraction. To quantify use of therapies, 7 individual metrics (use of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, β-blocker, aldosterone antagonist, anticoagulation, implantable cardioverter defibrillator, cardiac resynchronization therapy, and HF education) and composite metrics were assessed. Care metrics include only patients documented to be eligible and without contraindications or intolerance. Among practices, 69% were nonteaching. Patients were 71% male, with a median age of 70 years, and a median ejection fraction of 25%. Use of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (80%) and β-blocker (86%) was relatively high in eligible patients in the outpatient cardiology setting; other metrics, such as aldosterone antagonist (36%), device therapy (implantable cardioverter defibrillator/cardiac resynchronization therapy with defibrillator, 51%; cardiac resynchronization therapy, 39%), and education (61%), showed lower rates of use. A median 27% of patients received all HF therapies for which they were potentially eligible on the basis of chart documentation. Use of guideline-recommended therapies by practices varied widely. Conclusions— These data are among the first to assess treatment in the outpatient setting since the release of the latest national HF guidelines and to demonstrate substantial variation among cardiology practices in the documented therapies provided to HF patients.
Fonarow et al. (Thu,) conducted a cohort in chronic heart failure (n=15,381). Guideline-recommended heart failure therapies was evaluated on Use of 7 individual metrics of guideline-recommended therapies and composite metrics. In US outpatient cardiology practices, use of guideline-recommended heart failure therapies varied widely, with a median of 27% of eligible patients receiving all indicated therapies.