The rodent Psychomotor Vigilance Test (rPVT) successfully measures sustained attention in rats, showing high similarity to human PVT performances including lapses in attention and reaction times.
The rPVT is a valid preclinical tool for assessing sustained attention and fatigue in rodents, closely mirroring human PVT performance.
The human Psychomotor Vigilance Test (PVT) is a widely used procedure for measuring changes in fatigue and sustained attention. The present article describes a rodent version of the PVT-termed the "rPVT"-that measures similar aspects of attention (i.e., performance accuracy, motor speed, premature responding, and lapses in attention). Data are presented that demonstrate both the short- and long-term usefulness of the rPVT when employed with laboratory rats. Rats easily learn the rPVT, and learning to perform the basic procedure takes less than two weeks of training. Once acquired, rat performances in the rPVT show a high degree of similarity to these same performance measures in the human PVT, including similarities in, lapses in attention, reaction times, vigilance decrements across session time (i.e., the human "time-on-task" effects), and the response-stimulus interval (RSI) effect described for humans. Thus the rPVT can be an extremely valuable tool for assessing the effects of a wide range of variables on sustained attention quite similar to human PVT performances, and thus can be useful for developing novel treatments for neurobehavioral dysfunctions.
Davis et al. (Thu,) conducted a other in Neurobehavioral performance and sustained attention. Rodent Psychomotor Vigilance Test (rPVT) vs. Human PVT (conceptual comparison) was evaluated on Performance accuracy, motor speed, premature responding, and lapses in attention. The rodent Psychomotor Vigilance Test (rPVT) successfully measures sustained attention in rats, showing high similarity to human PVT performances including lapses in attention and reaction times.
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