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These data suggest that the loss of glycosylation of key uptake and efflux transporters in humans NASH may influence transporter function and contribute to altered drug disposition observed in NASH.
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John Clarke
Petr Novák
April D. Lake
Liver International
University of Arizona
Czech Academy of Sciences, Biology Centre
Institute of Plant Molecular Biology
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Clarke et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69dd4d5799c691022d99bf17 — DOI: https://doi.org/10.1111/liv.13362