Multiparametric cardiac magnetic resonance using the Lake Louise Criteria demonstrated a pooled diagnostic accuracy of 83% for diagnosing acute myocarditis, while T1 mapping showed an accuracy of 86%.
Does multi-parametric CMR accurately diagnose myocardial inflammation in patients with suspected myocarditis?
Multi-parametric CMR, particularly the combined Lake Louise Criteria and emerging parametric mapping techniques, provides a valuable non-invasive diagnostic tool for acute myocarditis.
Cardiac magnetic resonance (CMR) has changed the management of suspected viral myocarditis by providing a 'positive' diagnostic test and has lead to new insights into myocardial involvement in systemic inflammatory conditions. In this review we analyse the use of CMR tissue characterisation techniques across the available studies including T2 weighted imaging, early gadolinium enhancement, late gadolinium enhancement, Lake Louise Criteria, T2 mapping, T1 mapping and extracellular volume assessment. We also discuss the use of multiparametric CMR in acute cardiac transplant rejection and a variety of inflammatory conditions such as sarcoidosis, systemic lupus erythrematous, rheumatoid arthritis and systemic sclerosis.
Lagan et al. (Fri,) conducted a review in Myocarditis and systemic inflammatory diseases. Cardiac magnetic resonance (CMR) vs. Clinical diagnosis or endomyocardial biopsy was evaluated on Diagnostic accuracy for acute myocarditis. Multiparametric cardiac magnetic resonance using the Lake Louise Criteria demonstrated a pooled diagnostic accuracy of 83% for diagnosing acute myocarditis, while T1 mapping showed an accuracy of 86%.
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