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In this paper, we propose a simple and effective preprocessing method for melanoma classification by considering cytological properties of melanomas, in particular the alignment of the major axis of the tumor in the same direction. We evaluate our method with a set of 1,760 dermoscopic images (329 of melanomas and 1,431 of nevi) and a simple convolutional neural network (CNN) classifier with five-fold cross validation. The proposed tumor alignment method improves the classification performance by 5.8% in terms of the area under the ROC curve (AUC). In addition, it proves to be 2.1% better in term of AUC when compared with the same configured CNN trained using images that are nine times larger. Our results also show that considering the intrinsic features of the classification target is important even when the classifier has a capability to obtain effective features automatically through its learning process.
Yoshida et al. (Thu,) studied this question.