Balloon pulmonary angioplasty significantly improved quality of life, increasing the physical component summary score from 29.5 to 39.4, and improved hemodynamics in patients with CTEPH.
Observational (n=25)
No
Does balloon pulmonary angioplasty improve quality of life and hemodynamics in patients with chronic thromboembolic pulmonary hypertension?
Balloon pulmonary angioplasty provides significant improvements in quality of life alongside functional and hemodynamic benefits in patients with chronic thromboembolic pulmonary hypertension.
Absolute Event Rate: 39.4% vs 29.5%
p-value: p=0.001
BACKGROUND: The effect of balloon pulmonary angioplasty (BPA) on improvement in functional and hemodynamic parameters in chronic thromboembolic pulmonary hypertension (CTEPH) is known, but the quality of life (QoL) of patients treated with BPA has never been studied before. METHODS AND RESULTS: ; P=0.04), PVR (10.4±3.9 vs. 5.5±2.2 Wood units; P<0.05), functional class (96% vs. 20% in WHO class III and IV, P<0.05) and improvement in 6MWT distance (323±135 vs. 410±109 m; P<0.05) was observed. The only significant correlation was between the mental component summary score of QoL after completion of treatment and percentage improvement in the 6MWT (-0.404, P<0.05). CONCLUSIONS: Alongside improvement in functional and hemodynamic parameters, BPA also provides significant improvement in QoL.
Darocha et al. (Sun,) conducted a observational in Chronic Thromboembolic Pulmonary Hypertension (CTEPH) (n=25). Balloon pulmonary angioplasty (BPA) vs. Baseline (pre-BPA) was evaluated on Physical Component Summary (PCS) score on the SF-36v2 questionnaire (p=0.001). Balloon pulmonary angioplasty significantly improved quality of life, increasing the physical component summary score from 29.5 to 39.4, and improved hemodynamics in patients with CTEPH.
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