March 7, 2017The Egyptian Heart Journal9 citationsOpen Access

Clinical and laboratory characteristics of short-term mortality in Egyptian patients with acute heart failure

AAAhmad Tageldien Abdellah AMalaa mohamed HHHamdy Ali Hendawi

Structured PICO

Population

120 consecutive adult patients (≥18 years) presented with acute heart failure (AHF) and low LVEF to the emergency department of Suez Canal University hospital, Egypt. Mean age 59.3 ± 10.1 years, 55.8% male. Excluded: liver failure, cancer, renal failure on hemodialysis, post-traumatic shortness of breath, or acute coronary syndromes.

Outcome

Short-term mortality (mortality within 30 days of AHF presentation, either during admission or after hospital discharge)hard clinical

In Egyptian patients with acute heart failure, short-term mortality is high (24.16%) and can be predicted by clinical, laboratory, and echocardiographic parameters including low LVEF, dilated LV/LA, impaired kidney function, and low serum albumin.

Limitations

single center
limited number of consecutive recruited AHF patients
didn't include HF patients with preserved ejection fraction
long-term follow-up was not performed

Abstract

OBJECTIVE: To identify the clinical and laboratory predictors of short-term mortality in patients with acute heart failure (AHF). SUBJECTS AND METHODS: We conducted a prospective, single center study on 120 consecutive patients presented with acute heart failure to the emergency department. All patients had clinical, laboratory, electrocardiographic and echocardiographic evaluation. Short-term mortality was reported within 30 days of presentation. RESULTS: < 0.002).ROC curve analysis showed that low LVEF (≤24%), dilated LV end diastolic diameter (LVESD) ≥ 66.5 mm, dilated LV end systolic diameter (LVESD) ≥ 53.5 mm, dilated LA diameter ≥ 48 mm, increased serum creatinine ≥ 1.6 mg/dl, and decreased serum albumin ≤ 3 g/dl can significantly predict short-term mortality in patients with acute heart failure. CONCLUSION: Variable clinical, laboratory, electrocardiographic and echocardiographic parameters were associated with short-term mortality. Our study showed that low LVEF, dilated LV diameter, dilated LA diameter, impaired kidney function and low serum albumin can predict short-term mortality in patients with acute heart failure.

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