Intravenous streptokinase successfully resolved a large mitral prosthetic valve thrombus in a 40-year-old woman who presented with acute pulmonary edema four years after discontinuing anticoagulation.
Case Report (n=1)
No
Intravenous streptokinase successfully treated a rare case of mechanical mitral valve thrombosis in a patient who had survived 4 years without anticoagulation.
A 40 years lady who underwent a mitral valve replacement with a mechancial prosthesis nine years ago, stopped oral anticoagulants totally. She was asymptomatic and doing her field job with good exercise tolerance for 4 years without any anticoagulation or follow-up and presented now with acute pulmonary edema due to prosthetic valve thrombosis. Echocardiography revealed a large clot on the mitral valve and increased Doppler gradients across the valve. She was given intravenous streptokinase for 28 hours with relief of symptoms, re-appearance of prosthetic valve click and normalisation of flow velocities. She was prescribed oral acenocoumarol and discharged in a stable condition.
Chitrapu et al. (Thu,) conducted a case report in Mitral mechanical prosthetic valve thrombosis (n=1). Intravenous streptokinase was evaluated on Resolution of prosthetic valve thrombosis. Intravenous streptokinase successfully resolved a large mitral prosthetic valve thrombus in a 40-year-old woman who presented with acute pulmonary edema four years after discontinuing anticoagulation.