A 2-minute fingertip photoplethysmogram analytic program reliably identified atrial fibrillation with an area under the curve of 0.972, significantly outperforming a 1-minute program.
Observational (n=666)
No
Does quantitative analysis of fingertip photoplethysmogram (PPG) waveforms accurately identify atrial fibrillation in acute stroke patients?
Quantitative analysis of 2-minute fingertip photoplethysmogram waveforms can accurately identify atrial fibrillation in acute stroke patients, offering a potential convenient screening tool.
Absolute Event Rate: 0.972% vs 0.949%
p-value: p=<0.001
Atrial fibrillation (AF) detection is crucial for stroke prevention. We investigated the potential of quantitative analyses of photoplethysmogram (PPG) waveforms to identify AF. Continuous electrocardiogram (EKG) and fingertip PPG were recorded simultaneously in acute stroke patients (n = 666) admitted to an intensive care unit. Each EKG was visually labeled as AF (n = 150, 22.5%) or non-AF. Linear and nonlinear features from the pulse interval (PIN) and peak amplitude (AMP) of PPG waveforms were extracted from the first 1, 2, and 10 min of data. Logistic regression analysis revealed six independent PPG features feasibly identifying AF rhythm, including three PIN-related (mean, mean of standard deviation, and sample entropy), and three AMP-related features (mean of the root mean square of the successive differences, sample entropy, and turning point ratio) (all p < 0.01). The performance of the PPG analytic program comprising all 6 features that were extracted from the 2-min data was better than that from the 1-min data (area under the receiver operating characteristic curve was 0.972 (95% confidence interval 0.951-0.989) vs. 0.949 (0.929-0.970), p < 0.001 and was comparable to that from the 10-min data 0.973 (0.953-0.993) for AF identification. In summary, our study established the optimal PPG analytic program in reliably identifying AF rhythm.
Tang et al. (Mon,) conducted a observational in Atrial Fibrillation in Acute Stroke (n=666). 2-minute fingertip photoplethysmogram (PPG) analytic program vs. 1-minute fingertip photoplethysmogram (PPG) analytic program was evaluated on Area under the receiver operating characteristic curve for AF identification (95% CI 0.951-0.989, p=<0.001). A 2-minute fingertip photoplethysmogram analytic program reliably identified atrial fibrillation with an area under the curve of 0.972, significantly outperforming a 1-minute program.