Does warfarin reduce ischemic stroke and provide net clinical benefit in atrial fibrillation patients with liver cirrhosis?
Warfarin use in patients with atrial fibrillation and liver cirrhosis is associated with a lower risk of ischemic stroke and a positive net clinical benefit.
For atrial fibrillation patients with liver cirrhosis in the current analysis of an observational study, warfarin use was associated with a lower risk of ischemic stroke and a positive net clinical benefit compared with nontreatment, and thus, thromboprophylaxis should be considered for such patients.
Kuo et al. (Sat,) studied this question.