Permanent His-bundle pacing has emerged as the leading candidate for physiological pacing by providing nearly normal electrical activation of both ventricles and avoiding ventricular dyssynchrony.
What are the current physiological pacing options to avoid ventricular dyssynchrony in patients requiring cardiac pacing?
Patients with bradycardia due to sinus node dysfunction or atrioventricular block
Physiological pacing options, particularly His-bundle pacing
Traditional right ventricular (RV) apical pacing
Hemodynamic response and ventricular dyssynchrony
His-bundle pacing is highlighted as a leading physiological pacing strategy to prevent the deleterious effects of traditional RV apical pacing.
Cardiac pacing is an effective treatment for patients with bradycardia due to sinus node dysfunction or atrioventricular block. Despite decades of technological advances, the optimal ventricular pacing site to mimic normal human ventricular physiology and best hemodynamic response remains elusive. Beginning with atrial synchronous right ventricular (RV) apical pacing, the search has continued through alternate RV pacing sites, minimizing RV pacing, biventricular pacing, left ventricular (LV) pacing, and His-bundle pacing. Understanding the deleterious effects of long-term RV apical pacing in vulnerable populations has created tremendous interest in alternate pacing options. This paper reviews the current status of available pacing options, with particular focus on His-bundle pacing. Permanent His-bundle pacing has emerged as the leading candidate for physiological pacing because it provides nearly normal electrical activation of both ventricles and thereby avoids ventricular dyssynchrony. Synchronized LV pacing, multisite LV pacing, and LV endocardial pacing offer promise as novel pacing options in select patients.
Building similarity graph...
Analyzing shared references across papers
Loading...
Pugazhendhi Vijayaraman
Pierre Bordachar
Kenneth A. Ellenbogen
Journal of the American College of Cardiology
Virginia Commonwealth University
Hôpital Cardiologique du Haut-Lévêque
University Health System
Building similarity graph...
Analyzing shared references across papers
Loading...
Vijayaraman et al. (Thu,) conducted a review in Bradycardia due to sinus node dysfunction or atrioventricular block. His-bundle pacing was evaluated. Permanent His-bundle pacing has emerged as the leading candidate for physiological pacing by providing nearly normal electrical activation of both ventricles and avoiding ventricular dyssynchrony.
www.synapsesocial.com/papers/69e795638a4862ceef5c8dc7 — DOI: https://doi.org/10.1016/j.jacc.2017.05.005