Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia

Key Points

• To evaluate the efficacy of low-dose aspirin compared with placebo in reducing the incidence of preterm preeclampsia among pregnant individuals at high risk.
• Randomized, placebo-controlled clinical trial (EudraCT: 2013-003778-29, ISRCTN: ISRCTN13633058).
• Administered low-dose aspirin versus placebo to pregnant women identified as high risk for preterm preeclampsia.
• Treatment with low-dose aspirin resulted in a lower incidence of preterm preeclampsia compared to placebo.