Do depressive symptoms and diabetes distress affect glycaemic control and diabetes complications in newly diagnosed type 2 diabetes?
Depressive symptoms are associated with an increased incidence of macrovascular complications in the first 2 years after type 2 diabetes diagnosis, despite minimal effects on glycaemic control.
AIMS/HYPOTHESIS: We examined the associations between depressive symptoms and diabetes distress with glycaemic control and diabetes complications over 2 years, after diagnosis of type 2 diabetes. METHODS: as the primary outcome and with incident rates of diabetes complications as secondary outcomes. Multivariate models were used to account for potential confounders. RESULTS: or incident complications. CONCLUSIONS/INTERPRETATION: In the first 2 years of type 2 diabetes, the effect of depressive symptoms and diabetes distress on glycaemic control is minimal. There was, however, an association between depressive symptoms and incidence of macrovascular complications. Elevated innate inflammation may be common to both depression and macrovascular diabetes complications, but these findings require replication.
Ismail et al. (Thu,) studied this question.