Weak collateral circulation (Rentrop grade I-II) in chronic right coronary artery occlusion was associated with a greater stable perfusion defect compared to good collaterals (9.8% vs 4.1%).
Observational (n=90)
Does the grade of collateral circulation impact myocardial perfusion and function in patients with right coronary artery occlusion?
Better collateral circulation (Rentrop grade III) in chronic right coronary artery occlusion is associated with improved resting myocardial perfusion and longitudinal deformation compared to weak collaterals.
Absolute Event Rate: 9.8% vs 4.1%
Aim . To evaluate perfusion and functioning of myocardium in occluded coronary artery with various types of collateral blood flow. Material and methods. Ninety patients with three-vessel disease and obligate occlusion of the right coronary artery (RCA) according to the type of collateral flow development, were selected to 2 groups: first — 44 patients (49%) with I and II grades by Rentrop, second — 46 patients (51%) with grade III Rentrop collaterals. Perfusion scintigraphy data was analysed, with echocardiography and tissue Doppler. Results. Worsening of perfusion of myocardium inferior wall was found in patient of group 2 with non-significant defect of perfusion in 1st group patient. Stable perfusion defect in group 1 was 9,8±3,5%, in group 2 — 4,1±1,7%. While comparing tissue Doppler values, change in longitudinal deformation of inferior wall in the group with worse collaterals was -4,1±2,6, in group 2 -6,8±2,7. While assessing segmentary contractility of the inferior wall of the left ventricle, lower number of hypokinesis segments was found in group 2. Conclusion . Chronic occlusion of coronary artery with a weak collaterals is followed by worse parameters of local perfusion and function of myocardium. In a good condition of collaterals, regardless the non-significant perfusion disorders in myocardium at rest, there are prominent stress-defects and local contractility disorders of myocardium.
Fomichev et al. (Sun,) conducted a observational in Three-vessel disease and obligate occlusion of the right coronary artery (n=90). Weak collateral circulation (Rentrop grade I and II) vs. Good collateral circulation (Rentrop grade III) was evaluated on Stable perfusion defect. Weak collateral circulation (Rentrop grade I-II) in chronic right coronary artery occlusion was associated with a greater stable perfusion defect compared to good collaterals (9.8% vs 4.1%).