Atrial fibrillation is associated with significantly increased mean left atrial wall thickness (1.7 vs. 1.1 mm) and total pulmonary vein cross-sectional area (1052 vs. 809 mm2) compared to healthy controls.
Cross-Sectional (n=94)
No
Does left atrial wall thickness and pulmonary vein size differ in patients with atrial fibrillation compared to healthy controls?
Patients with atrial fibrillation have significantly increased left atrial wall thickness and pulmonary vein size compared to healthy controls, which may reflect atrial remodeling and inform individualized catheter ablation strategies.
Absolute Event Rate: 1.7% vs 1.1%
p-value: p=<0.0001
Atrial Fibrillation (AF) is the most common cardiac arrhythmia and a cause of increased morbidity and mortality. Left Atrial (LA) tissue characteristics play an important role in the pathogenesis of AF. Catheter ablation of AF has emerged as a popular treatment option, however predictors of treatment success are not clearly defined. For a better understanding of the LA structural organization we noninvasively characterized Left Atrial Wall Thickness (LAWT) and Pulmonary Vein Cross-Sectional Area (PVCSA) using Multidetector Computed Tomography (MDCT) in AF patients and healthy controls.
Anna F. Thomsen (Fri,) conducted a cross-sectional in Atrial Fibrillation (n=94). Atrial Fibrillation vs. Healthy controls was evaluated on Mean Left Atrial Wall Thickness (LAWT) in mm (p=<0.0001). Atrial fibrillation is associated with significantly increased mean left atrial wall thickness (1.7 vs. 1.1 mm) and total pulmonary vein cross-sectional area (1052 vs. 809 mm2) compared to healthy controls.
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