Does the combined measurement of left atrial area plus reverse longitudinal strain rate and/or IVRT provide an accurate assessment of diastolic function in mouse models of heart disease?
Combined echocardiographic measurements of left atrial area, reverse longitudinal strain rate, and IVRT effectively assess diastolic function and distinguish pathophysiology in mouse models of heart disease.
These results indicate that the combined measurement of left atrial area plus reverse longitudinal strain rate and/or IVRT provide an excellent overall assessment of diastolic function in the diseased mouse heart, allowing distinction between different types of pathophysiology.
Schnelle et al. (Thu,) studied this question.