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O. This protocol has been successfully applied to the high incorporation of deuterium and tritium in 18 drug molecules, which meet the requirements for use in ligand-binding assays and absorption, distribution, metabolism, and excretion studies.
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Yong Yao Loh
Kazunori Nagao
Andrew J. Hoover
Science
Princeton University
Merck & Co., Inc., Rahway, NJ, USA (United States)
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Loh et al. (Thu,) studied this question.
www.synapsesocial.com/papers/6a01afa61adb974501caf0ef — DOI: https://doi.org/10.1126/science.aap9674
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