Does IVF/ICSI conception increase the risk of congenital heart defects compared to spontaneous conception?
IVF/ICSI conception is associated with an increased risk of congenital heart defects compared to spontaneous conception, though significant heterogeneity exists.
Fetuses conceived with IVF/ICSI methods are at an increased risk of developing CHD compared with those conceived spontaneously. However, this finding deserves further investigation due to heterogeneity of both ART procedures and cardiac defects. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.
Giorgione et al. (Wed,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: