The difference between pulmonary venous and mitral A wave durations (Ardur - Adur) correlated significantly with invasively measured left ventricular end-diastolic pressure (r=0.675, p<0.001).
Observational (n=100)
No
Do echocardiographic Doppler indices accurately correlate with invasively measured left ventricular end diastolic pressure in patients with coronary artery disease?
Echocardiographic Doppler indices, particularly the difference between pulmonary venous and mitral A wave durations, provide a reliable noninvasive estimate of left ventricular filling pressures in CAD patients regardless of systolic function.
Effect estimate: r = 0.675
p-value: p=<0.001
In patients with coronary heart disease, evaluation of the left ventricular end diastolic pressure (LVEDP) provides assessment of the hemodynamic severity and aids in assessing the prognosis, and in deciding the proper management and therapeutic interventions. It also helps to distinguish this syndrome from other diseases such as pulmonary disease that can result in dyspnoea. The early diastolic doppler indexes derived from transmitral flow velocity curves correlated significantly with LV filling pressures in patients with systolic dysfunction, but the correlation was weak in patients with preserved systolic function. The difference between the pulmonary venous and mitral A durations correlated well with LVEDP in patients with CAD, irrespective of the systolic function. In this study we found echocardiographic doppler derived transmitral and pulmonary venous flow indices can be used as a safe and noninvasive means of predicting the LV filling pressures in patients with coronary artery disease, especially in patients with LV systolic dysfunction, as an alternative to the invasive measurements obtained during cardiac catheterization.
Kushaal Vikram (Wed,) conducted a observational in Coronary Artery Disease (n=100). Echocardiographic Doppler parameters vs. Cardiac catheterization (LVEDP) was evaluated on Correlation of the difference between pulmonary venous and mitral A wave durations (Ardur - Adur) with LVEDP (r = 0.675, p=<0.001). The difference between pulmonary venous and mitral A wave durations (Ardur - Adur) correlated significantly with invasively measured left ventricular end-diastolic pressure (r=0.675, p<0.001).