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METTL3 is frequently up-regulated in human HCC and contributes to HCC progression. METTL3 represses SOCS2 expression in HCC through an m6A-YTHDF2-dependent mechanism. Our findings suggest an important mechanism of epigenetic alteration in liver carcinogenesis. (Hepatology 2018;67:2254-2270).
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Mengnuo Chen
Lai Wei
Cheuk‐Ting Law
Hepatology
University of Hong Kong
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Chen et al. (Fri,) studied this question.
www.synapsesocial.com/papers/69d7e2ebec32c73b01ae32d3 — DOI: https://doi.org/10.1002/hep.29683
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