Catheter ablation for persistent and long-standing persistent atrial fibrillation with restoration of sinus rhythm significantly improves major indices of hemodynamic and functional status.
Does catheter ablation improve rhythm control and functional status in patients with persistent and long-standing persistent atrial fibrillation?
Successful catheter ablation of persistent and long-standing persistent AF, especially when achieving sinus rhythm, yields significant hemodynamic and functional benefits, supporting its use beyond just symptom control.
Persistent and long-standing persistent atrial fibrillation evolves from complex arrhythmogenic substrate and sources. Multiple studies have shown improved freedom from arrhythmia recurrences if sinus rhythm had been restored during the index ablation; however, such harder procedural endpoint requires laborious stepwise approach almost invariably pursuing non-pulmonary-vein sources. Longer-term conversion of persistent atrial fibrillation into sinus rhythm is associated with significant improvement in major indices of hemodynamic and functional status; these indices also represent major predictors of cardiovascular mortality. Optimal ablation techniques and strategies preserving most of the individual potential for functional improvement need to be established.
Martin Fiala (Fri,) conducted a review in Persistent and Long-Standing Persistent Atrial Fibrillation. Catheter ablation was evaluated. Catheter ablation for persistent and long-standing persistent atrial fibrillation with restoration of sinus rhythm significantly improves major indices of hemodynamic and functional status.
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