A fixed-point iterative algorithm enabled a partitioned numerical solution of the myocardium and Purkinje network electromechanical coupling, successfully simulating a heartbeat.
This computational study demonstrates a novel numerical approach for simulating the electromechanical coupling of the left ventricle and Purkinje network during a heartbeat.
In this work, we consider the numerical approximation of the electromechanical coupling in the left ventricle with inclusion of the Purkinje network. The mathematical model couples the 3D elastodynamics and bidomain equations for the electrophysiology in the myocardium with the 1D monodomain equation in the Purkinje network. For the numerical solution of the coupled problem, we consider a fixed-point iterative algorithm that enables a partitioned solution of the myocardium and Purkinje network problems. Different levels of myocardium-Purkinje network splitting are considered and analyzed. The results are compared with those obtained using standard strategies proposed in the literature to trigger the electrical activation. Finally, we present a numerical study that, although performed in an idealized computational domain, features all the physiological issues that characterize a heartbeat simulation, including the initiation of the signal in the Purkinje network and the systolic and diastolic phases.
Landajuela et al. (Sun,) conducted a other in Electromechanical coupling in the left ventricle. Fixed-point iterative algorithm for partitioned solution vs. Standard strategies to trigger electrical activation was evaluated. A fixed-point iterative algorithm enabled a partitioned numerical solution of the myocardium and Purkinje network electromechanical coupling, successfully simulating a heartbeat.
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