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∼0.25-0.30) and show high positive correlation, indicating they may be good measurements of host resistance to AGD. While the genetic architecture of resistance appeared to be largely polygenic in nature, two regions on chromosome 18 showed suggestive association with both AGD resistance traits. Using a cross-validation approach, genomic prediction accuracy was up to 18% higher than that obtained using pedigree, and a reduction in marker density to ∼2,000 SNPs was sufficient to obtain accuracies similar to those obtained using the whole dataset. This study indicates that resistance to AGD is a suitable trait for genomic selection, and the addition of this trait to Atlantic salmon breeding programs can lead to more resistant stocks.
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Diego Robledo
Oswald Matika
Alastair Hamilton
G3 Genes Genomes Genetics
University of Edinburgh
Roslin Institute
Hendrix Genetics (Netherlands)
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Robledo et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69fd274354949f8cfd5d133a — DOI: https://doi.org/10.1534/g3.118.200075
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