Atrial fibrillation in inherited cardiomyopathies is reviewed regarding its prevalence, pathophysiology, risk factors, and treatment challenges across different cardiomyopathy subtypes.
This review highlights the prevalence, pathophysiology, and challenging management of atrial fibrillation in patients with inherited cardiomyopathies.
Atrial fibrillation (AF) often complicates the course of inherited cardiomyopathies and, in some cases, may be the presenting feature. Each inherited cardiomyopathy has its own peculiar pathogenetic characteristics that can contribute to the development and maintenance of AF. Atrial fibrillation may occur as a consequence of disease-specific defects, non-specific cardiac chamber changes secondary to the primary illness, or a combination thereof. The presence of AF can denote a turning point in the progression of the disease, promoting clinical deterioration and increasing morbidity and mortality. Furthermore, the management of AF can be particularly challenging in patients with inherited cardiomyopathies. In this article, we review the current information on the prevalence, pathophysiology, risk factors, and treatment of AF in three different inherited cardiomyopathies: hypertrophic cardiomyopathy, arrhythmogenic right ventricular dysplasia/cardiomyopathy, familial dilated cardiomyopathy, and left ventricular non-compaction cardiomyopathy.
Yeung et al. (Thu,) conducted a review in Atrial fibrillation in inherited cardiomyopathies. Atrial fibrillation in inherited cardiomyopathies is reviewed regarding its prevalence, pathophysiology, risk factors, and treatment challenges across different cardiomyopathy subtypes.