Planning Study Size Based on Precision Rather Than Power

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Abstract

Study size has typically been planned based on statistical power and therefore has been heavily influenced by the philosophy of statistical hypothesis testing. A worthwhile alternative is to plan study size based on precision, for example by aiming to obtain a desired width of a confidence interval for the targeted effect. This article presents formulas for planning the size of an epidemiologic study based on the desired precision of the basic epidemiologic effect measures.

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Authors

Kenneth J. Rothman

Boston University

Sander Greenland

Boston University

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Epidemiology

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University of California, Los Angeles

Boston University

RTI International

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Rothman et al. (Fri,) studied this question.

synapsesocial.com/papers/6a1fc884e2f0a48241989847 — DOI: https://doi.org/10.1097/ede.0000000000000876

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Disengaging from statistical significance· 2016 · 72 citations
The tyranny of power: is there a better way to calculate sample size?· 2009 · 135 citations
ON SAMPLE-SIZE AND POWER CALCULATIONS FOR STUDIES USING CONFIDENCE INTERVALS· 1988 · 86 citations
That Confounded P-Value· 1998 · 328 citations
Nonsignificance Plus High Power Does Not Imply Support for the Null Over the Alternative· 2012 · 94 citations

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Disengaging from statistical significance· 2016 · 72 citations
The tyranny of power: is there a better way to calculate sample size?· 2009 · 135 citations
ON SAMPLE-SIZE AND POWER CALCULATIONS FOR STUDIES USING CONFIDENCE INTERVALS· 1988 · 86 citations
That Confounded P-Value· 1998 · 328 citations
Nonsignificance Plus High Power Does Not Imply Support for the Null Over the Alternative· 2012 · 94 citations

Planning Study Size Based on Precision Rather Than Power

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Abstract

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Discussion

Authors

Journals

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Institutions

References and Citations

Citation Network

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Discussion

Cite this study

Also consider

Also consider