Improvements in guideline-directed treatment for acute coronary syndromes over 15 years in Portugal were accompanied by a reduction in in-hospital mortality from 6.7% in 2002 to 2.5% in 2016.
Observational (n=45,141)
Yes
Over 15 years, improved compliance with guidelines and increased primary PCI use in Portugal were associated with a significant reduction in in-hospital ACS mortality.
Absolute Event Rate: 2.5% vs 6.7%
The Portuguese Registry of Acute Coronary Syndromes (ProACS) has completed 15 years of continuous and prospective activity. We present an overall picture of the data from this powerful tool. Up to 2016, 45 141 records were included, mostly male (71%), and with a mean age of 66 years. Baseline characteristics remained stable over the years. Of the overall population, 44% of cases were ST-elevation myocardial infarction (STEMI). Over the years there was a significant improvement in compliance with international guidelines, in terms of both diagnostic and therapeutic procedures, as well as for medication. In particular, the rate of reperfusion in STEMI increased to 84%, mainly by primary percutaneous coronary intervention (only 5.2% were treated by thrombolysis in 2016). By contrast, timings in STEMI did not change significantly. Improvements in treatment were accompanied by a reduction in in-hospital mortality from 6.7% in 2002 to 2.5% in 2016 in the overall population. This registry enables analysis of the management and results of acute coronary syndromes over time in Portugal, and hence assessment of improvements in quality of care.
Timóteo et al. (Sun,) conducted a observational in Acute Coronary Syndromes (n=45,141). Temporal trends in acute coronary syndrome management vs. Historical comparison (2002 vs 2016) was evaluated on In-hospital mortality. Improvements in guideline-directed treatment for acute coronary syndromes over 15 years in Portugal were accompanied by a reduction in in-hospital mortality from 6.7% in 2002 to 2.5% in 2016.