Patients with HFpEF and PVD exhibit distinct haemodynamic limitations during exercise, highlighting a specific pathophysiologic phenotype that requires targeted therapeutic interventions.
Heart failure with preserved ejection fraction patients with PVD demonstrate unique haemodynamic limitations during exercise that constrain aerobic capacity, including impaired recruitment of LV preload due to excessive right heart congestion and blunted RV systolic reserve. Interventions targeted to this distinct pathophysiology require testing in patients with HFpEF and PVD.
Gorter et al. (Tue,) studied this question.
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