July 2, 2018
View Full PaperScreening for undiagnosed atrial fibrillation
Key Result
While atrial fibrillation screening is simple and low risk, additional research is needed to determine whether it ultimately reduces stroke and stroke-related complications and costs.
Structured PICO
Does atrial fibrillation screening reduce stroke and stroke-related complications?
P
Population
Patients at risk for undiagnosed atrial fibrillation
I
Intervention
Atrial fibrillation screening
While AF screening is simple and low cost, further research is needed to determine if it effectively reduces stroke and related complications.
Limitations
- Need for validation of new technologies and devices
- Need to define strategies for linking screening with initiation of oral anticoagulation therapy
- Uncertainty regarding whether screening ultimately reduces stroke and stroke-related complications and costs
Abstract
INTRODUCTION: Atrial fibrillation (AF) is a condition of global importance, and it is associated with significant morbidity, mortality, and healthcare costs. A considerable proportion of patients with AF are asymptomatic, and stroke may be the first clinical manifestation of their AF diagnosis. AF screening provides an opportunity to identify patients with undetected AF prior to suffering a devastating complication. Areas covered: This review will provide a rationale for AF screening; summarize AF screening methods, studies, and economic analyses; evaluate AF as a condition meeting criteria for population screening; and discuss potential drawbacks. Expert commentary: While AF screening is simple, low risk, and, in most cases, low cost, additional research is needed validating new technologies and devices; defining strategies for linking screening with initiation of oral anticoagulation therapy and determining whether AF screening ultimately reduces stroke and stroke-related complications and costs.