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The use of maintenance therapy with olaparib provided a substantial benefit with regard to progression-free survival among women with newly diagnosed advanced ovarian cancer and a BRCA1/2 mutation, with a 70% lower risk of disease progression or death with olaparib than with placebo. (Funded by AstraZeneca and Merck; SOLO1 ClinicalTrials.gov number, NCT01844986 .).
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Kathleen N. Moore
Nicoletta Colombo
Giovanni Scambia
New England Journal of Medicine
Dana-Farber Cancer Institute
Memorial Sloan Kettering Cancer Center
UNSW Sydney
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Moore et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69d6c49aa0177bf533ed8eb5 — DOI: https://doi.org/10.1056/nejmoa1810858