Arterial pressure is determined by cardiac output, systemic vascular resistance, and critical closing pressure, requiring consideration of tissue perfusion rather than just pressure targets.
Blood pressure physiology
Measurement of arterial pressure is one of the most basic elements of patient management. Arterial pressure is determined by the volume ejected by the heart into the arteries, the elastance of the walls of the arteries, and the rate at which the blood flows out of the arteries. This review will discuss the three forces that determine the pressure in a vessel: elastic, kinetic, and gravitational energy. Emphasis will be placed on the importance of the distribution of arterial resistances, the elastance of the walls of the large vessels, and critical closing pressures in small arteries and arterioles. Regulation of arterial pressure occurs through changes in cardiac output and changes in vascular resistance, but these two controlled variables can sometimes be in conflict.
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Sheldon Magder
General Cardiology
Critical Care
McGill University Health Centre
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Sheldon Magder (Thu,) conducted a review in Blood pressure physiology. Arterial pressure is determined by cardiac output, systemic vascular resistance, and critical closing pressure, requiring consideration of tissue perfusion rather than just pressure targets.
synapsesocial.com/papers/6a1ed1136e6b94f521a46037 — DOI: https://doi.org/10.1186/s13054-018-2171-1