Two cases of Carney complex presented with multiple bone lesions showing mixed osteosclerotic and osteolytic patterns on imaging, highly suggestive of osteochondromyxoma.
Case Report (n=2)
Detailed analysis of the imaging manifestations of bone lesions may help in the recognition of Carney complex, a rare syndrome associated with cardiac myxomas.
Carney complex (CNC) is an extremely rare genetic syndrome of pigmented skin lesions, endocrine hyperfunction and myxoma. Given its diverse clinical manifestations, CNC is often misdiagnosed. Recognition of some special clinical manifestations and imaging features may help with the diagnosis. Early diagnosis of CNC would alert ongoing surveillance of tumors and complications; the prognosis of CNC may thus be improved by early treatment. Herein, we report two cases of CNC with bone lesions.
Li et al. (Sat,) conducted a case report in Carney complex with bone lesions (n=2). Clinical observation and imaging was evaluated on Clinical and imaging features of bone lesions. Two cases of Carney complex presented with multiple bone lesions showing mixed osteosclerotic and osteolytic patterns on imaging, highly suggestive of osteochondromyxoma.