Nurse-led motivational telephone follow-up did not improve adherence to P2Y12 inhibitors at 30 days (95% vs 93%, P=0.627), but reduced hospital readmissions (8% vs 16%, P=0.048).
RCT (n=294)
1:1
Does a nurse-led motivational telephone follow-up improve adherence to P2Y12 inhibitors and self-management in elective patients undergoing same-day discharge PCI?
A nurse-led motivational telephone follow-up 2-5 days after same-day PCI discharge does not improve short-term antiplatelet adherence but significantly reduces hospital readmissions and unplanned healthcare contacts.
Absolute Event Rate: 95% vs 93%
p-value: p=.627
BACKGROUND: Same-day discharge of patients undergoing percutaneous coronary intervention (PCI) may challenge preparation of patients for discharge. OBJECTIVE: The objective of this study was to investigate whether nurse-led telephone follow-up influenced patients' self-management post-PCI. METHODS: We performed a randomized study with an allocation rate of 1:1. A standardized nurse-led motivational telephone consultation was conducted between 2 and 5 days after PCI to support adherence to medical therapy, follow-up activities, emotional well-being, and healthy lifestyle. The control group received usual care and discharge procedures. Primary outcome was adherence to use of P2Y12 inhibitor (clopidogrel or ticagrelor) therapy at 30 days of follow-up. RESULTS: We consecutively included 294 elective patients (83%) undergoing PCI and with planned same-day discharge. Adherence to P2Y12 inhibitors was not influenced by the intervention (intervention vs control, 95% vs 93%, respectively; P = .627). However, the proportion of patients readmitted (8% vs 16%, P = .048), as well as self-initiated contacts to general practitioners (29% vs 42%, P = .020), was lower in the intervention group compared with the control group. Patients in the intervention group were more likely to know how to manage symptoms of angina pectoris (90% vs 80%, P = .015), and a higher proportion of patients in the intervention group commenced healthy physical activities (53% vs 41%, P = .043). CONCLUSION: Nurse-led motivational telephone follow-up did not influence adherence to antiplatelet medical therapy after PCI. However, the intervention positively influenced self-management of angina pectoris and reduced hospital readmissions and self-initiated contacts to general practitioners and hospitals.
Mols et al. (Thu,) conducted a rct in Percutaneous coronary intervention (n=294). Nurse-led motivational telephone follow-up vs. Usual care and discharge procedures was evaluated on Adherence to use of P2Y12 inhibitor (clopidogrel or ticagrelor) therapy at 30 days of follow-up (p=.627). Nurse-led motivational telephone follow-up did not improve adherence to P2Y12 inhibitors at 30 days (95% vs 93%, P=0.627), but reduced hospital readmissions (8% vs 16%, P=0.048).
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