Fetal magnetocardiography in 132 normal pregnancies showed that P, PR, QRS, and RR intervals increased with gestational age, and U-waves were present in 11% of fetuses.
Observational (n=132)
What are the normal fetal magnetocardiogram waveform characteristics in healthy fetuses?
This study establishes prediction intervals for fMCG waveform intervals and amplitudes in normal fetuses, which is critical for identifying fetuses with abnormal rhythm.
BACKGROUND: Fetal magnetocardiography (fMCG) is the most direct and precise method of assessing fetal rhythm and conduction. Although the utility of fMCG for evaluation of fetuses with serious arrhythmia is generally acknowledged, many aspects of fetal rhythm and conduction are relatively unstudied. OBJECTIVE: To record fMCG in a large group of normal fetuses in order to provide a more comprehensive evaluation of fMCG waveform characteristics, including waveform intervals, amplitudes, and morphology. METHODS: The subjects were 132 healthy women with uncomplicated singleton pregnancies, studied at 15.7-39.9 (mean 28.9) weeks' gestation in 259 sessions. The P, PR, QRS, QT, QTc, and RR intervals and the P/QRS and T/QRS amplitude ratios were measured. MAIN RESULTS: The P, PR, QRS, and RR intervals increased with gestational age, but QT and QTc did not. U-waves were seen in 11% of fetuses. The T-waves were often flat with low T/QRS amplitude ratios. Equiphasic QRS complexes were associated with tall P-waves. The PR, QRS, and QT intervals showed a power law dependence on RR interval with power law exponents 0.445, 0.363, and 0.381, respectively. SIGNIFICANCE: The data establish prediction intervals for fMCG waveform intervals and amplitudes in normal fetuses. This is critical for identification of fetuses with abnormal rhythm. Our study is the first to document the incidence of U-waves and flat T-waves in the fetus, both of which are uncommon postnatally. The association of tall P-waves with equiphasic QRS complexes provides a useful means of improving the resolution of fetal P-waves.
Strand et al. (Mon,) conducted a observational in Normal fetuses (n=132). Fetal magnetocardiography (fMCG) was evaluated on fMCG waveform characteristics including waveform intervals, amplitudes, and morphology. Fetal magnetocardiography in 132 normal pregnancies showed that P, PR, QRS, and RR intervals increased with gestational age, and U-waves were present in 11% of fetuses.