March 5, 2019Open Access

Multi-Omics Profiling Reveals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer

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Abstract

Our study represents a step toward personalized immunotherapy for patients with TNBC. Immune checkpoint inhibitors might be effective for "immune-inflamed" cluster, and the transformation of "cold tumors" into "hot tumors" should be considered for "immune-desert" and "innate immune-inactivated" clusters.

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Authors

Yi Xiao

Ding Ma

Shen Zhao

Journals

Clinical Cancer Research

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Institutions

Chinese Academy of Sciences

Fudan University Shanghai Cancer Center

Shanghai Advanced Research Institute

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Multi-Omics Profiling Reveals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer

Key Points

Abstract

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Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

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Discussion

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